As someone who has been researching various treatments for Chronic Idiopathic Urticaria (CIU), I recently came across Cyproheptadine as a potential solution. It's an antihistamine that is known to help control and reduce the severity of hives and itching caused by CIU. What's interesting is that it also has anticholinergic and serotonin antagonist properties, which could provide additional benefits in managing this condition. From what I've gathered, Cyproheptadine can be a useful treatment option for those who haven't found relief with other antihistamines. I'm hopeful that this medication could potentially help many people suffering from CIU to finally find some relief.